Serveur d'exploration sur la grippe en France

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Economic burden of seasonal influenza B in France during winter 2010-2011.

Identifieur interne : 000240 ( Main/Exploration ); précédent : 000239; suivant : 000241

Economic burden of seasonal influenza B in France during winter 2010-2011.

Auteurs : Maria Laura Silva [France] ; Lionel Perrier ; Hans-Martin Sp Th ; Isidore Grog ; Anne Mosnier ; Nathalie Havet ; Jean Marie Cohen

Source :

RBID : pubmed:24443900

Descripteurs français

English descriptors

Abstract

BACKGROUND

In France, 2-15% of the population is affected annually by influenza, which causes significant socioeconomic disruption. Nevertheless, despite its importance for policy makers, few published studies have evaluated the impact of influenza B. Therefore, we assessed the costs associated with influenza B during 2010-2011 in France.

METHODS

Cases of lab-confirmed influenza B were analyzed as part of the Influenza B in General Practice Study. Cost calculations were based on micro-costing methods according to the French Health Insurance (FHI) perspective (in Euros, 2011). Costs were compared between age groups using the Kruskal-Wallis test, and when significant, by multiple comparisons based on rank. Moreover, uncertainties were assessed using one-way sensitivity and probabilistic analyses. Overall economic burden was estimated by multiplying cost per patient, flu attack rate, and the French population.

RESULTS

A total of 201 patients were included in the study. We found that the mean cost associated with Influenza B was 72€ (SD: 205) per patient: 70€ (SD: 262) for younger children, 50€ (SD: 195) for older children, 126€ (SD: 180) for adults, and 42€ (SD: 18) for elderly. Thus, we observed significantly different costs between the distinct age groups (p<0.0001). Finally, the economic burden of influenza B for the FHI was estimated to be 145 million Euros (95% CI: 88-201).

CONCLUSIONS

Our findings highlight the important impact of influenza B and encourage further investigation on policy regarding vaccination strategies in France.


DOI: 10.1186/1471-2458-14-56
PubMed: 24443900
PubMed Central: PMC3909302


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

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<term>Grippe humaine (économie)</term>
<term>Grippe humaine (épidémiologie)</term>
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<b>BACKGROUND</b>
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<p>In France, 2-15% of the population is affected annually by influenza, which causes significant socioeconomic disruption. Nevertheless, despite its importance for policy makers, few published studies have evaluated the impact of influenza B. Therefore, we assessed the costs associated with influenza B during 2010-2011 in France.</p>
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<p>
<b>METHODS</b>
</p>
<p>Cases of lab-confirmed influenza B were analyzed as part of the Influenza B in General Practice Study. Cost calculations were based on micro-costing methods according to the French Health Insurance (FHI) perspective (in Euros, 2011). Costs were compared between age groups using the Kruskal-Wallis test, and when significant, by multiple comparisons based on rank. Moreover, uncertainties were assessed using one-way sensitivity and probabilistic analyses. Overall economic burden was estimated by multiplying cost per patient, flu attack rate, and the French population.</p>
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<p>
<b>RESULTS</b>
</p>
<p>A total of 201 patients were included in the study. We found that the mean cost associated with Influenza B was 72€ (SD: 205) per patient: 70€ (SD: 262) for younger children, 50€ (SD: 195) for older children, 126€ (SD: 180) for adults, and 42€ (SD: 18) for elderly. Thus, we observed significantly different costs between the distinct age groups (p<0.0001). Finally, the economic burden of influenza B for the FHI was estimated to be 145 million Euros (95% CI: 88-201).</p>
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<b>CONCLUSIONS</b>
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<p>Our findings highlight the important impact of influenza B and encourage further investigation on policy regarding vaccination strategies in France.</p>
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<Citation>Vaccine. 2010 Sep 7;28 Suppl 4:D45-53</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">20713260</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
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<ArticleIdList>
<ArticleId IdType="pubmed">21215340</ArticleId>
</ArticleIdList>
</Reference>
<Reference>
<Citation>Vaccine. 2012 Feb 27;30(10):1895-900</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">22222872</ArticleId>
</ArticleIdList>
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<Reference>
<Citation>Hum Vaccin Immunother. 2012 Jan;8(1):81-8</Citation>
<ArticleIdList>
<ArticleId IdType="pubmed">22252006</ArticleId>
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<Reference>
<Citation>Pharmacoeconomics. 2001;19(3):223-30</Citation>
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<ArticleId IdType="pubmed">11303411</ArticleId>
</ArticleIdList>
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<affiliations>
<list>
<country>
<li>France</li>
</country>
<region>
<li>Auvergne-Rhône-Alpes</li>
<li>Rhône-Alpes</li>
</region>
<settlement>
<li>Lyon</li>
</settlement>
</list>
<tree>
<noCountry>
<name sortKey="Cohen, Jean Marie" sort="Cohen, Jean Marie" uniqKey="Cohen J" first="Jean Marie" last="Cohen">Jean Marie Cohen</name>
<name sortKey="Grog, Isidore" sort="Grog, Isidore" uniqKey="Grog I" first="Isidore" last="Grog">Isidore Grog</name>
<name sortKey="Havet, Nathalie" sort="Havet, Nathalie" uniqKey="Havet N" first="Nathalie" last="Havet">Nathalie Havet</name>
<name sortKey="Mosnier, Anne" sort="Mosnier, Anne" uniqKey="Mosnier A" first="Anne" last="Mosnier">Anne Mosnier</name>
<name sortKey="Perrier, Lionel" sort="Perrier, Lionel" uniqKey="Perrier L" first="Lionel" last="Perrier">Lionel Perrier</name>
<name sortKey="Sp Th, Hans Martin" sort="Sp Th, Hans Martin" uniqKey="Sp Th H" first="Hans-Martin" last="Sp Th">Hans-Martin Sp Th</name>
</noCountry>
<country name="France">
<region name="Auvergne-Rhône-Alpes">
<name sortKey="Silva, Maria Laura" sort="Silva, Maria Laura" uniqKey="Silva M" first="Maria Laura" last="Silva">Maria Laura Silva</name>
</region>
</country>
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</affiliations>
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